Promise to Progress

The National Institutes of Health's All of Us Research Program is a historic effort to collect and study data from a million or more people living in the United States. The goal of All of Us is to speed up health research discoveries, enabling new kinds of individualized health care.

To make this possible, the program is building one of the world's largest and most diverse databases for health research. The program seeks for its participant cohort to reflect the diversity of the U.S. population.

Our history

In 2015, the National Institutes of Health (NIH) formed a precision medicine working group with the goal of advancing precision medicine for all. Three years later, the NIH officially opened participant enrollment in the All of Us Research Program. More than 774,000 participants have enrolled in the program as of March 2024.

Because of participants’ generous contributions of data, All of Us was able to launch the Researcher Workbench in 2020. Through this platform, thousands of researchers are conducting health research with the All of Us dataset.

The promise of precision medicine continues to drive this program forward. In 2022, All of Us began returning personalized health-related DNA results to participants, so that they can learn about their own health.

The program continues to grow. Last year, more than 157,000 participants enrolled in All of Us and nearly 4,000 researchers registered to use the Researcher Workbench.

774,000+

Participants

431,000+

Electronic Health Records

532,000+

Participants who have completed initial steps of the program

554,000+

Biosamples

How the promise of precision medicine inspires participants and researchers

The research featured at the All of Us Researchers Convention is made possible by our participants and researchers. Watch the videos below to hear their stories.

Karl Cooper and Dr. Stephen Sodeke reflect on transparency and inclusion in health research.

Karl Cooper is the Director of Public Health Programs at the American Association on Health and Disability, an All of Us partner. Cooper talks about why he joined All of Us and the importance of inclusivity in medical research.

Tuskegee University Professor of Bioethics and All of Us Resource Access Board Co-Chair Stephen O. Sodeke, PhD, discusses the importance of transparency in research and how to build trust with communities that have been historically underrepresented in biomedical research.

Venus Gines and Ky'Era Actkins share how All of Us can power women's health research.

Venus Gines reflects on how losing her sister to cervical cancer led her to become an All of Us participant and shares why joining the program was important to her.

Ky'Era Actkins, PhD, NIH postdoctoral research fellow, shares what sparked her research on women’s health and her interest in health disparities research.

How the Researcher Workbench is advancing precision medicine research

The All of Us Researcher Workbench is a secure, cloud-based platform that houses All of Us data. The program offers tiered access to the data. Researchers’ institutions must first have agreements in place with All of Us before they can register to use the Researcher Workbench.

These are some of the ways that researchers are using the All of Us Researcher Workbench to advance health research.

Counting the Steps to Lower Diabetes Risk with All of Us

Being active can help prevent many diseases, including type 2 diabetes. Looking at Fitbit data from All of Us participants, researchers found that taking at least 10,700 steps a day was linked to a lower risk of type 2 diabetes. The results suggest a lifestyle practice that people can take to help prevent diabetes.

Read more here

All of Us Data Highlights Risky Drinking Among Cancer Survivors

A new study of All of Us survey data found that most participants who are cancer survivors drink alcohol regularly, even during treatment. Many drink heavily, often, or both. The results indicate a need to find ways to help cancer survivors drink less alcohol.

Read more here

All of Us Data Shows the Power of Social Support to Prevent Depression

We know social support is good for mental health, especially during hard times. In a new study, researchers looked at specific types of social support during COVID-19. Thanks to All of Us, the researchers learned which types protected against depression the most and which groups benefited the most from social support.

Read more here

Learning more about LGBTQIA+ Health Thanks to All of Us

Researchers studying All of Us data found that anxiety, depression, HIV diagnosis, and tobacco use disorder were more common in LGBTQIA+ participants than in non-LGBTQIA+ participants. Rates of other conditions varied among LGBTQIA+ groups. This study shows that All of Us data can help us learn more about LGBTQIA+ health and health inequities.

Read more here

Visit the convention agenda to explore even more research powered by All of Us data.